Case report: Chronic Candida albicans meningitis: a rare entity diagnosed by metagenomic next-generation sequencing

Case report: Chronic Candida albicans meningitis: a rare entity diagnosed by metagenomic next-generation sequencing

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The aetiology of chronic aseptic meningitis is difficult to establish.Candida meningitis in particular is often diagnosed late, as cerebrospinal fluid (CSF) work-up and imaging findings are nonspecific.A 35-year-old patient with chronic aseptic meningitis, for which Cooktop repeated microbiological testing of CSF was unrevealing, was finally diagnosed with Candida albicans (C.albicans) meningitis with LG GSL760MCXV American-Style Smart Fridge Freezer - Black cauda equina involvement using metagenomic next-generation sequencing (mNGS).

This report highlights the diagnostic challenges and the difficulties of treating shunt-associated fungal meningitis.